Grignard Reaction

The Grignard Reaction Synthesis of triphenylmethanol Josh Wilson Chem 443-003 January 1,2012-February 7,2012 Introduction In this prove we synthesized triphenylmethanol from a Grignard reagent and an ester. To form triphenylmethanol we reacted methyl benzoate with phenylmagnesium bromide. Reaction Scheme: system An organo aluminiferous compound is an original compound that contains a ampere-second-metallic bond. The metal flush toilet be Li, Na, Mg, Cu, Pd or any other transitional metal. In this laboratory we used Mg as our metallic portion of the organometallic compound. Organometallic compounds be special in that they cause Carbon to become a nucleophile. More specifically in this lab we used R-Mg-Br an alkyl magnesium halide to project the nucleophillic properties onto the Carbon atom, know as a Grignard reagent because of it founder chemist Victor Grignard. The dissolve of Grignard reactions is to create a C-C bond, more specifically a ordinal or a secondary alcohol. The Grignard reagents argon usually created with the solvents anhydrous diethyl aether or THF and are very air sensitive. The Grignard reagent are very prefatory which make them very good proton acceptors. In our experiment we created a third alcohol by victimization an ester and carbonyl molecule.

The ester is born-again to a ketone than immediately reacts with the Grignard reagent to give the tertiary alcohol, triphenylmethanol. Reaction machine Procedure A. Preparation of the Grignard reagent * Weigh intimately .5 g of Magnesium turnings * engage mortar and pastel to labor turnings * Put tu! nings into around layabout flask * Assemble setup * Prepare 2.4 mL of bromobenzene in 5 mL of anhydrous diethyl ether * Swirl mixture, than add 5mL to round bottom flask * Reflux reaction * Add .5 mL increments of the impractical dissolver over 10 minutes B. Synthesis of Triphenylmethanol * Dissolve 1.2 mL of methyl benzoate in 5 mL of anhydrous diethyl ether *...If you call for to get a full essay, order it on our website: OrderCustomPaper.com

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